GO Annotations Graph

• Symbol: Duoxa1
• Name: dual oxidase maturation factor 1
• ID: MGI:2384861

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:164475
Cellular Component	GO:0031252	cell leading edge	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:164475
Biological Process	GO:0042743	hydrogen peroxide metabolic process	IGI	J:205165
Biological Process	GO:0010729	positive regulation of hydrogen peroxide biosynthetic process	ISO	J:164563
Biological Process	GO:0045666	positive regulation of neuron differentiation	IMP	J:164475
Biological Process	GO:0045666	positive regulation of neuron differentiation	IDA	J:164475
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	IGI	J:164475
Biological Process	GO:0008104	protein localization	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0015031	protein transport	IEA	J:72247
Biological Process	GO:0050727	regulation of inflammatory response	IGI	J:205165
Biological Process	GO:2000609	regulation of thyroid hormone generation	IGI	J:205329