GO Annotations Graph

• Symbol: Cdk5rap2
• Name: CDK5 regulatory subunit associated protein 2
• ID: MGI:2384875

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005516	calmodulin binding	ISO	J:164563
Molecular Function	GO:0005516	calmodulin binding	IBA	J:265628
Molecular Function	GO:0043015	gamma-tubulin binding	ISO	J:164563
Molecular Function	GO:0043015	gamma-tubulin binding	IBA	J:265628
Molecular Function	GO:0008017	microtubule binding	ISO	J:164563
Molecular Function	GO:0008017	microtubule binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:160692
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IBA	J:265628
Molecular Function	GO:0015631	tubulin binding	ISO	J:164563
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0005813	centrosome	IDA	J:160692
Cellular Component	GO:0005813	centrosome	IDA	J:163849
Cellular Component	GO:0005813	centrosome	IDA	J:240425
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005813	centrosome	IDA	J:126953
Cellular Component	GO:0005813	centrosome	IDA	J:178978
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0000931	gamma-tubulin ring complex	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005874	microtubule	ISO	J:164563
Cellular Component	GO:0005815	microtubule organizing center	IEA	J:72247
Cellular Component	GO:0035371	microtubule plus-end	ISO	J:164563
Cellular Component	GO:0035371	microtubule plus-end	IBA	J:265628
Cellular Component	GO:0097431	mitotic spindle pole	IBA	J:265628
Cellular Component	GO:0097431	mitotic spindle pole	IDA	J:226309
Cellular Component	GO:0000242	pericentriolar material	ISO	J:164563
Cellular Component	GO:0000242	pericentriolar material	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IBA	J:265628
Cellular Component	GO:0000922	spindle pole	ISO	J:164563
Biological Process	GO:0007420	brain development	IMP	J:160533
Biological Process	GO:0007099	centriole replication	ISO	J:164563
Biological Process	GO:0007099	centriole replication	IBA	J:265628
Biological Process	GO:0007098	centrosome cycle	ISO	J:164563
Biological Process	GO:0007059	chromosome segregation	ISO	J:164563
Biological Process	GO:0007059	chromosome segregation	IBA	J:265628
Biological Process	GO:0000132	establishment of mitotic spindle orientation	IMP	J:160533
Biological Process	GO:0000132	establishment of mitotic spindle orientation	IBA	J:265628
Biological Process	GO:0001578	microtubule bundle formation	ISO	J:164563
Biological Process	GO:0001578	microtubule bundle formation	IBA	J:265628
Biological Process	GO:0000226	microtubule cytoskeleton organization	ISO	J:164563
Biological Process	GO:0031023	microtubule organizing center organization	ISO	J:164563
Biological Process	GO:0046600	negative regulation of centriole replication	IMP	J:163849
Biological Process	GO:0046600	negative regulation of centriole replication	IBA	J:265628
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:155856
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:160692
Biological Process	GO:0022008	neurogenesis	IMP	J:160533
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0031116	positive regulation of microtubule polymerization	ISO	J:164563
Biological Process	GO:0031116	positive regulation of microtubule polymerization	IBA	J:265628
Biological Process	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	ISO	J:164563
Biological Process	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	IBA	J:265628