GO Annotations Graph

• Symbol: Ccm2
• Name: cerebral cavernous malformation 2
• ID: MGI:2384924

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:146528
Molecular Function	GO:0005515	protein binding	IPI	J:187714
Molecular Function	GO:0005515	protein binding	IPI	J:187714
Molecular Function	GO:0005515	protein binding	IPI	J:146528
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	IDA	J:146528
Biological Process	GO:0001568	blood vessel development	IMP	J:146528
Biological Process	GO:0060837	blood vessel endothelial cell differentiation	IMP	J:146528
Biological Process	GO:0045216	cell-cell junction organization	IMP	J:146528
Biological Process	GO:0001885	endothelial cell development	IGI	J:146528
Biological Process	GO:0001885	endothelial cell development	IMP	J:146528
Biological Process	GO:0061154	endothelial tube morphogenesis	ISO	J:146528
Biological Process	GO:0003158	endothelium development	NAS	J:320403
Biological Process	GO:0007507	heart development	IBA	J:265628
Biological Process	GO:0007507	heart development	IMP	J:146528
Biological Process	GO:0007507	heart development	ISO	J:146528
Biological Process	GO:0007507	heart development	IGI	J:146528
Biological Process	GO:0001701	in utero embryonic development	IMP	J:146528
Biological Process	GO:0001701	in utero embryonic development	IGI	J:146528
Biological Process	GO:0048839	inner ear development	IDA	J:174607
Biological Process	GO:0035264	multicellular organism growth	IMP	J:146528
Biological Process	GO:0035264	multicellular organism growth	IGI	J:146528
Biological Process	GO:0060039	pericardium development	IMP	J:146528
Biological Process	GO:0060039	pericardium development	IGI	J:146528
Biological Process	GO:0045765	regulation of angiogenesis	NAS	J:320403
Biological Process	GO:0001944	vasculature development	IGI	J:146528
Biological Process	GO:0001944	vasculature development	IMP	J:146528
Biological Process	GO:0001570	vasculogenesis	ISO	J:164563
Biological Process	GO:0001570	vasculogenesis	IBA	J:265628
Biological Process	GO:0001570	vasculogenesis	IGI	J:146528
Biological Process	GO:0048845	venous blood vessel morphogenesis	IMP	J:146528
Biological Process	GO:0048845	venous blood vessel morphogenesis	IMP	J:146528
Biological Process	GO:0048845	venous blood vessel morphogenesis	IGI	J:146528