GO Annotations Graph

• Symbol: Wrap53
• Name: WD repeat containing, antisense to Trp53
• ID: MGI:2384933

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042393	histone binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0051087	protein-folding chaperone binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	IBA	J:265628
Molecular Function	GO:0070034	telomerase RNA binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0015030	Cajal body	ISO	J:164563
Cellular Component	GO:0015030	Cajal body	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0035861	site of double-strand break	ISO	J:164563
Cellular Component	GO:0005697	telomerase holoenzyme complex	ISO	J:164563
Biological Process	GO:0030576	Cajal body organization	ISO	J:164563
Biological Process	GO:0030576	Cajal body organization	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0045739	positive regulation of DNA repair	ISO	J:164563
Biological Process	GO:2000781	positive regulation of double-strand break repair	ISO	J:164563
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	ISO	J:164563
Biological Process	GO:1904851	positive regulation of establishment of protein localization to telomere	ISO	J:164563
Biological Process	GO:0051973	positive regulation of telomerase activity	ISO	J:164563
Biological Process	GO:0051973	positive regulation of telomerase activity	IDA	J:263490
Biological Process	GO:1904867	protein localization to Cajal body	ISO	J:164563
Biological Process	GO:0034337	RNA folding	ISO	J:164563
Biological Process	GO:0090666	scaRNA localization to Cajal body	ISO	J:164563
Biological Process	GO:0090671	telomerase RNA localization to Cajal body	ISO	J:164563
Biological Process	GO:0032203	telomere formation via telomerase	ISO	J:164563
Biological Process	GO:0007004	telomere maintenance via telomerase	ISO	J:164563