GO Annotations Graph

• Symbol: Lemd2
• Name: LEM domain containing 2
• ID: MGI:2385045

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IBA	J:265628
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005635	nuclear envelope	ISO	J:164563
Cellular Component	GO:0005637	nuclear inner membrane	ISO	J:73065
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0031965	nuclear membrane	IDA	J:105608
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Biological Process	GO:0060914	heart formation	IMP	J:221495
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IBA	J:265628
Biological Process	GO:0043409	negative regulation of MAPK cascade	IMP	J:153986
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IMP	J:221495
Biological Process	GO:0022008	neurogenesis	IMP	J:221495
Biological Process	GO:0006998	nuclear envelope organization	ISO	J:164563
Biological Process	GO:0006998	nuclear envelope organization	IBA	J:265628
Biological Process	GO:0071168	protein localization to chromatin	ISO	J:164563
Biological Process	GO:1902531	regulation of intracellular signal transduction	IEA	J:72247
Biological Process	GO:0035914	skeletal muscle cell differentiation	ISO	J:73065
Biological Process	GO:0035914	skeletal muscle cell differentiation	IMP	J:153986