GO Annotations Graph

• Symbol: Lims2
• Name: LIM and senescent cell antigen like domains 2
• ID: MGI:2385067

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	IBA	J:265628
Cellular Component	GO:0005925	focal adhesion	IDA	J:82868
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0098609	cell-cell adhesion	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	IGI	J:167114
Biological Process	GO:0045216	cell-cell junction organization	IBA	J:265628
Biological Process	GO:0045216	cell-cell junction organization	IGI	J:167114
Biological Process	GO:1990705	cholangiocyte proliferation	IGI	J:207543
Biological Process	GO:0007229	integrin-mediated signaling pathway	IGI	J:167114
Biological Process	GO:0043066	negative regulation of apoptotic process	IGI	J:207543
Biological Process	GO:1904055	negative regulation of cholangiocyte proliferation	IGI	J:207543
Biological Process	GO:2000346	negative regulation of hepatocyte proliferation	IGI	J:207543
Biological Process	GO:2000178	negative regulation of neural precursor cell proliferation	IGI	J:208112
Biological Process	GO:2000178	negative regulation of neural precursor cell proliferation	IGI	J:208112
Biological Process	GO:0061351	neural precursor cell proliferation	IGI	J:208112
Biological Process	GO:0061351	neural precursor cell proliferation	IGI	J:208112
Biological Process	GO:2001046	positive regulation of integrin-mediated signaling pathway	IBA	J:265628
Biological Process	GO:2001046	positive regulation of integrin-mediated signaling pathway	IGI	J:167114
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	IBA	J:265628