GO Annotations Graph

• Symbol: Farp2
• Name: FERM, RhoGEF and pleckstrin domain protein 2
• ID: MGI:2385126

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008092	cytoskeletal protein binding	IEA	J:72247
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IDA	J:196400
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	TAS	Reactome:R-MMU-421147
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IBA	J:265628
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:79193
Cellular Component	GO:0005737	cytoplasm	ISO	J:79193
Cellular Component	GO:0005856	cytoskeleton	IEA	J:72247
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-421140
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-421147
Biological Process	GO:0031532	actin cytoskeleton reorganization	IMP	J:166376
Biological Process	GO:0007155	cell adhesion	IMP	J:166376
Biological Process	GO:0022405	hair cycle process	IMP	J:232539
Biological Process	GO:0016322	neuron remodeling	ISO	J:79193
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:166376
Biological Process	GO:0071800	podosome assembly	IMP	J:166376
Biological Process	GO:0016601	Rac protein signal transduction	ISO	J:79193
Biological Process	GO:0033623	regulation of integrin activation	IMP	J:166376
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	IMP	J:166376