GO Annotations Graph

• Symbol: Rap1gds1
• Name: RAP1, GTP-GDP dissociation stimulator 1
• ID: MGI:2385189

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030695	GTPase regulator activity	IDA	J:298386
Molecular Function	GO:0030695	GTPase regulator activity	IMP	J:298386
Molecular Function	GO:0030695	GTPase regulator activity	IMP	J:298386
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IDA	J:298386
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0086098	angiotensin-activated signaling pathway involved in heart process	IMP	J:287816
Biological Process	GO:0086098	angiotensin-activated signaling pathway involved in heart process	IMP	J:298386
Biological Process	GO:0080120	CAAX-box protein maturation	ISO	J:164563
Biological Process	GO:0003300	cardiac muscle hypertrophy	IMP	J:298386
Biological Process	GO:0002534	cytokine production involved in inflammatory response	IMP	J:287816
Biological Process	GO:0002534	cytokine production involved in inflammatory response	IMP	J:298386
Biological Process	GO:0031034	myosin filament assembly	ISO	J:155856
Biological Process	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration	ISO	J:164563
Biological Process	GO:0034260	negative regulation of GTPase activity	IMP	J:287816
Biological Process	GO:0034260	negative regulation of GTPase activity	IMP	J:298386
Biological Process	GO:0034260	negative regulation of GTPase activity	IDA	J:298386
Biological Process	GO:0034260	negative regulation of GTPase activity	IMP	J:298386
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:155856
Biological Process	GO:0043547	positive regulation of GTPase activity	IBA	J:265628
Biological Process	GO:0051561	positive regulation of mitochondrial calcium ion concentration	ISO	J:164563
Biological Process	GO:0034504	protein localization to nucleus	ISO	J:164563
Biological Process	GO:0070376	regulation of ERK5 cascade	IMP	J:298386
Biological Process	GO:0070376	regulation of ERK5 cascade	IMP	J:298386
Biological Process	GO:1904464	regulation of matrix metallopeptidase secretion	IMP	J:287816
Biological Process	GO:0010821	regulation of mitochondrion organization	ISO	J:164563
Biological Process	GO:0036273	response to statin	IMP	J:298386
Biological Process	GO:0014829	vascular associated smooth muscle contraction	ISO	J:155856