GO Annotations Graph

• Symbol: Gtf2b
• Name: general transcription factor IIB
• ID: MGI:2385191

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016407	acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0016407	acetyltransferase activity	IBA	J:265628
Molecular Function	GO:0016746	acyltransferase activity	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IDA	J:138818
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0004402	histone acetyltransferase activity	IEA	J:72245
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	ISO	J:164563
Molecular Function	GO:1990841	promoter-specific chromatin binding	ISO	J:164563
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:181994
Molecular Function	GO:0005515	protein binding	IPI	J:209693
Molecular Function	GO:0005515	protein binding	IPI	J:86566
Molecular Function	GO:0000993	RNA polymerase II complex binding	ISO	J:164563
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	ISO	J:164563
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	IBA	J:265628
Molecular Function	GO:0017025	TBP-class protein binding	ISO	J:164563
Molecular Function	GO:0017025	TBP-class protein binding	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0032153	cell division site	IDA	J:209693
Cellular Component	GO:0005694	chromosome	ISO	J:164563
Cellular Component	GO:0000793	condensed chromosome	IDA	J:209693
Cellular Component	GO:0042585	germinal vesicle	IDA	J:209693
Cellular Component	GO:0000776	kinetochore	IDA	J:209693
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:209693
Cellular Component	GO:0005634	nucleus	IDA	J:181952
Cellular Component	GO:0005634	nucleus	IDA	J:138818
Cellular Component	GO:0032993	protein-DNA complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0005669	transcription factor TFIID complex	ISO	J:164563
Cellular Component	GO:0097550	transcription preinitiation complex	IBA	J:265628
Biological Process	GO:0051276	chromosome organization	IMP	J:209693
Biological Process	GO:0006352	DNA-templated transcription initiation	IEA	J:72247
Biological Process	GO:0009790	embryo development	IMP	J:209693
Biological Process	GO:0010467	gene expression	IMP	J:209693
Biological Process	GO:0051177	meiotic sister chromatid cohesion	IMP	J:209693
Biological Process	GO:1904798	positive regulation of core promoter binding	ISO	J:164563
Biological Process	GO:0006473	protein acetylation	ISO	J:164563
Biological Process	GO:0006473	protein acetylation	IBA	J:265628
Biological Process	GO:1990114	RNA polymerase II core complex assembly	ISO	J:164563
Biological Process	GO:1990114	RNA polymerase II core complex assembly	IBA	J:265628
Biological Process	GO:0051123	RNA polymerase II preinitiation complex assembly	ISO	J:164563
Biological Process	GO:0051123	RNA polymerase II preinitiation complex assembly	IBA	J:265628
Biological Process	GO:0051225	spindle assembly	IMP	J:209693
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006367	transcription initiation at RNA polymerase II promoter	ISO	J:164563
Biological Process	GO:0006367	transcription initiation at RNA polymerase II promoter	IBA	J:265628
Biological Process	GO:0070897	transcription preinitiation complex assembly	IEA	J:72247
Biological Process	GO:0001174	transcriptional start site selection at RNA polymerase II promoter	ISO	J:164563
Biological Process	GO:0001174	transcriptional start site selection at RNA polymerase II promoter	IBA	J:265628
Biological Process	GO:0019083	viral transcription	ISO	J:164563