GO Annotations Graph

• Symbol: Kmt5c
• Name: lysine methyltransferase 5C
• ID: MGI:2385262

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0042393	histone binding	IDA	J:211428
Molecular Function	GO:0042799	histone H4K20 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0042799	histone H4K20 methyltransferase activity	IBA	J:265628
Molecular Function	GO:0042799	histone H4K20 methyltransferase activity	IDA	J:223575
Molecular Function	GO:0042799	histone H4K20 methyltransferase activity	IDA	J:90491
Molecular Function	GO:0140944	histone H4K20 monomethyltransferase activity	IEA	J:72245
Molecular Function	GO:0140941	histone H4K20me methyltransferase activity	IEA	J:72245
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:1904047	S-adenosyl-L-methionine binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000779	condensed chromosome, centromeric region	IDA	J:90491
Cellular Component	GO:0000792	heterochromatin	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005721	pericentric heterochromatin	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0034772	histone H4-K20 dimethylation	IEA	J:72247
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	ISO	J:164563
Biological Process	GO:0045830	positive regulation of isotype switching	IMP	J:280470