GO Annotations Graph

• Symbol: Tardbp
• Name: TAR DNA binding protein
• ID: MGI:2387629

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	ISO	J:164563
Molecular Function	GO:0140693	molecular condensate scaffold activity	ISO	J:164563
Molecular Function	GO:0003730	mRNA 3'-UTR binding	ISO	J:164563
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0097157	pre-mRNA intronic binding	IDA	J:240782
Molecular Function	GO:0005515	protein binding	IPI	J:292536
Molecular Function	GO:0005515	protein binding	IPI	J:250353
Molecular Function	GO:0005515	protein binding	IPI	J:190257
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	IBA	J:265628
Molecular Function	GO:0003723	RNA binding	IDA	J:240782
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:186828
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0035061	interchromatin granule	ISO	J:155856
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0016607	nuclear speck	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:250353
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005726	perichromatin fibrils	ISO	J:155856
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	ISO	J:164563
Biological Process	GO:0070935	3'-UTR-mediated mRNA stabilization	ISO	J:164563
Biological Process	GO:1990000	amyloid fibril formation	ISO	J:164563
Biological Process	GO:0010467	gene expression	IMP	J:240782
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0043922	negative regulation by host of viral transcription	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0071765	nuclear inner membrane organization	ISO	J:164563
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:155856
Biological Process	GO:0042307	positive regulation of protein import into nucleus	IDA	J:250353
Biological Process	GO:0042981	regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0042752	regulation of circadian rhythm	IMP	J:283196
Biological Process	GO:0010468	regulation of gene expression	IBA	J:265628
Biological Process	GO:0031647	regulation of protein stability	ISO	J:164563
Biological Process	GO:0031647	regulation of protein stability	IMP	J:283196
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0008380	RNA splicing	ISO	J:164563
Biological Process	GO:0008380	RNA splicing	IMP	J:240782