GO Annotations Graph

• Symbol: Otop1
• Name: otopetrin 1
• ID: MGI:2388363

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015252	proton channel activity	IDA	J:259123
Molecular Function	GO:0015252	proton channel activity	ISO	J:164563
Molecular Function	GO:0015252	proton channel activity	TAS	Reactome:R-MMU-9729538
Molecular Function	GO:0015252	proton channel activity	IBA	J:265628
Cellular Component	GO:0016020	membrane	IDA	J:82639
Cellular Component	GO:0005886	plasma membrane	IDA	J:259123
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9729538
Biological Process	GO:0031214	biomineral tissue development	IEA	J:60000
Biological Process	GO:0032869	cellular response to insulin stimulus	IMP	J:229138
Biological Process	GO:0009590	detection of gravity	IMP	J:82639
Biological Process	GO:0009590	detection of gravity	IMP	J:82639
Biological Process	GO:0042472	inner ear morphogenesis	IBA	J:265628
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:82639
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:82639
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0060336	negative regulation of type II interferon-mediated signaling pathway	IMP	J:229138
Biological Process	GO:1902600	proton transmembrane transport	IDA	J:259123
Biological Process	GO:1902600	proton transmembrane transport	ISO	J:164563
Biological Process	GO:1902600	proton transmembrane transport	IBA	J:265628