GO Annotations Graph

• Symbol: Brms1
• Name: breast cancer metastasis-suppressor 1
• ID: MGI:2388804

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042826	histone deacetylase binding	IBA	J:265628
Molecular Function	GO:0051059	NF-kappaB binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:85083
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	NAS	J:243422
Cellular Component	GO:0016580	Sin3 complex	NAS	J:243422
Cellular Component	GO:0070822	Sin3-type complex	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0016575	histone deacetylation	IBA	J:265628
Biological Process	GO:0030336	negative regulation of cell migration	NAS	J:320045
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:1902455	negative regulation of stem cell population maintenance	NAS	J:243422
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NAS	J:320044
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NAS	J:320043
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	NAS	J:320045
Biological Process	GO:2000210	positive regulation of anoikis	ISO	J:164563
Biological Process	GO:0090312	positive regulation of protein deacetylation	ISO	J:164563
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	NAS	J:243422
Biological Process	GO:0042981	regulation of apoptotic process	ISO	J:164563