GO Annotations Graph

• Symbol: Dock1
• Name: dedicator of cytokinesis 1
• ID: MGI:2429765

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:127717
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0017124	SH3 domain binding	IEA	J:60000
Molecular Function	GO:0031267	small GTPase binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0016477	cell migration	IDA	J:98248
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	IGI	J:202604
Biological Process	GO:0007520	myoblast fusion	IBA	J:265628
Biological Process	GO:0006909	phagocytosis	IEA	J:60000
Biological Process	GO:0010634	positive regulation of epithelial cell migration	ISO	J:164563
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	ISO	J:164563
Biological Process	GO:0007264	small GTPase mediated signal transduction	IEA	J:72247