GO Annotations Graph

• Symbol: Sctr
• Name: secretin receptor
• ID: MGI:2441720

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008528	G protein-coupled peptide receptor activity	IBA	J:265628
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0042277	peptide binding	ISO	J:155856
Molecular Function	GO:0017046	peptide hormone binding	ISO	J:164563
Molecular Function	GO:0017046	peptide hormone binding	IBA	J:265628
Molecular Function	GO:0015055	secretin receptor activity	ISO	J:155856
Molecular Function	GO:0015055	secretin receptor activity	ISO	J:164563
Molecular Function	GO:0015055	secretin receptor activity	IDA	J:281249
Molecular Function	GO:0015055	secretin receptor activity	IBA	J:265628
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Cellular Component	GO:0005881	cytoplasmic microtubule	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007420	brain development	IBA	J:265628
Biological Process	GO:0007166	cell surface receptor signaling pathway	IEA	J:72247
Biological Process	GO:0002024	diet induced thermogenesis	IDA	J:281249
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0009992	intracellular water homeostasis	IMP	J:121376
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	IDA	J:281249
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:0050996	positive regulation of lipid catabolic process	IDA	J:281249
Biological Process	GO:0050996	positive regulation of lipid catabolic process	IMP	J:208291
Biological Process	GO:0032098	regulation of appetite	IDA	J:281249
Biological Process	GO:0032098	regulation of appetite	IMP	J:273530
Biological Process	GO:0048167	regulation of synaptic plasticity	IMP	J:114853
Biological Process	GO:0070295	renal water absorption	IMP	J:121376
Biological Process	GO:0031667	response to nutrient levels	IDA	J:281249
Biological Process	GO:0007165	signal transduction	IEA	J:60000