GO Annotations Graph

• Symbol: Ghsr
• Name: growth hormone secretagogue receptor
• ID: MGI:2441906

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	ISO	J:164563
Molecular Function	GO:0001616	growth hormone secretagogue receptor activity	ISO	J:155856
Molecular Function	GO:0001616	growth hormone secretagogue receptor activity	ISO	J:164563
Molecular Function	GO:0001616	growth hormone secretagogue receptor activity	IBA	J:265628
Molecular Function	GO:0016520	growth hormone-releasing hormone receptor activity	ISO	J:164563
Molecular Function	GO:0042562	hormone binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0017046	peptide hormone binding	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	ISO	J:155856
Cellular Component	GO:0097060	synaptic membrane	ISO	J:155856
Biological Process	GO:0008154	actin polymerization or depolymerization	ISO	J:164563
Biological Process	GO:0008343	adult feeding behavior	IMP	J:104704
Biological Process	GO:0032869	cellular response to insulin stimulus	IDA	J:129482
Biological Process	GO:0046697	decidualization	ISO	J:164563
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0036321	ghrelin secretion	ISO	J:155856
Biological Process	GO:0030252	growth hormone secretion	IGI	J:89243
Biological Process	GO:0009755	hormone-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0009755	hormone-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	IMP	J:89243
Biological Process	GO:0007611	learning or memory	ISO	J:155856
Biological Process	GO:0032099	negative regulation of appetite	ISO	J:155856
Biological Process	GO:0050728	negative regulation of inflammatory response	ISO	J:164563
Biological Process	GO:0046676	negative regulation of insulin secretion	ISO	J:121019
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	ISO	J:164563
Biological Process	GO:0032715	negative regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:0090327	negative regulation of locomotion involved in locomotory behavior	ISO	J:155856
Biological Process	GO:2000110	negative regulation of macrophage apoptotic process	ISO	J:155856
Biological Process	GO:0010700	negative regulation of norepinephrine secretion	ISO	J:155856
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:155856
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0032100	positive regulation of appetite	IMP	J:104704
Biological Process	GO:1904000	positive regulation of eating behavior	ISO	J:155856
Biological Process	GO:0045923	positive regulation of fatty acid metabolic process	ISO	J:155856
Biological Process	GO:0045927	positive regulation of growth	ISO	J:155856
Biological Process	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	IMP	J:89243
Biological Process	GO:0040018	positive regulation of multicellular organism growth	ISO	J:164563
Biological Process	GO:0120058	positive regulation of small intestinal transit	ISO	J:155856
Biological Process	GO:1904349	positive regulation of small intestine smooth muscle contraction	ISO	J:155856
Biological Process	GO:1903672	positive regulation of sprouting angiogenesis	ISO	J:155856
Biological Process	GO:1905564	positive regulation of vascular endothelial cell proliferation	ISO	J:155856
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0060259	regulation of feeding behavior	ISO	J:155856
Biological Process	GO:1905333	regulation of gastric motility	ISO	J:155856
Biological Process	GO:0060123	regulation of growth hormone secretion	ISO	J:155856
Biological Process	GO:0043134	regulation of hindgut contraction	ISO	J:155856
Biological Process	GO:0098696	regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	ISO	J:155856
Biological Process	GO:0099175	regulation of postsynapse organization	ISO	J:155856
Biological Process	GO:0051963	regulation of synapse assembly	IMP	J:117370
Biological Process	GO:0051969	regulation of transmission of nerve impulse	ISO	J:155856
Biological Process	GO:0032094	response to food	IDA	J:129482
Biological Process	GO:0009725	response to hormone	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IEA	J:60000