GO Annotations Graph

• Symbol: Bank1
• Name: B cell scaffold protein with ankyrin repeats 1
• ID: MGI:2442120

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043274	phospholipase binding	ISO	J:164563
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:1990782	protein tyrosine kinase binding	ISO	J:164563
Molecular Function	GO:1990782	protein tyrosine kinase binding	IBA	J:265628
Molecular Function	GO:0035591	signaling adaptor activity	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Biological Process	GO:0042113	B cell activation	ISO	J:164563
Biological Process	GO:0042113	B cell activation	IBA	J:265628
Biological Process	GO:0032635	interleukin-6 production	IMP	J:207126
Biological Process	GO:0000165	MAPK cascade	IMP	J:207126
Biological Process	GO:0050869	negative regulation of B cell activation	IBA	J:265628
Biological Process	GO:0050869	negative regulation of B cell activation	IGI	J:113321
Biological Process	GO:0032715	negative regulation of interleukin-6 production	IMP	J:207126
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IBA	J:265628
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IGI	J:113321
Biological Process	GO:0045947	negative regulation of translational initiation	IMP	J:207126
Biological Process	GO:0043410	positive regulation of MAPK cascade	IMP	J:207126
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0043491	protein kinase B signaling	IGI	J:113321
Biological Process	GO:0009617	response to bacterium	IEP	J:190322
Biological Process	GO:0007165	signal transduction	IEA	J:72247