GO Annotations Graph

• Symbol: Gak
• Name: cyclin G associated kinase
• ID: MGI:2442153

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0030276	clathrin binding	IBA	J:265628
Molecular Function	GO:0030332	cyclin binding	ISO	J:155856
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:127098
Molecular Function	GO:0005515	protein binding	IPI	J:97384
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:72245
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0031982	vesicle	ISO	J:164563
Cellular Component	GO:0031982	vesicle	IBA	J:265628
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0048268	clathrin coat assembly	ISO	J:164563
Biological Process	GO:0072318	clathrin coat disassembly	ISO	J:164563
Biological Process	GO:0072318	clathrin coat disassembly	IBA	J:265628
Biological Process	GO:0072318	clathrin coat disassembly	IGI	J:158574
Biological Process	GO:0072583	clathrin-dependent endocytosis	ISO	J:164563
Biological Process	GO:0072583	clathrin-dependent endocytosis	IBA	J:265628
Biological Process	GO:0072583	clathrin-dependent endocytosis	IMP	J:158574
Biological Process	GO:0072583	clathrin-dependent endocytosis	IMP	J:180119
Biological Process	GO:0007029	endoplasmic reticulum organization	IMP	J:180119
Biological Process	GO:0009913	epidermal cell differentiation	IMP	J:180119
Biological Process	GO:0002064	epithelial cell development	IMP	J:180119
Biological Process	GO:0061436	establishment of skin barrier	IMP	J:180119
Biological Process	GO:0048853	forebrain morphogenesis	IMP	J:180119
Biological Process	GO:0048853	forebrain morphogenesis	IMP	J:180119
Biological Process	GO:0048853	forebrain morphogenesis	IMP	J:180119
Biological Process	GO:0048853	forebrain morphogenesis	IMP	J:180119
Biological Process	GO:0048853	forebrain morphogenesis	IMP	J:180119
Biological Process	GO:0007030	Golgi organization	ISO	J:164563
Biological Process	GO:0007030	Golgi organization	IMP	J:180119
Biological Process	GO:0090160	Golgi to lysosome transport	ISO	J:164563
Biological Process	GO:0035622	intrahepatic bile duct development	IMP	J:180119
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:180119
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:180119
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:180119
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:180119
Biological Process	GO:0010977	negative regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0061351	neural precursor cell proliferation	IMP	J:180119
Biological Process	GO:0061351	neural precursor cell proliferation	IMP	J:180119
Biological Process	GO:0061351	neural precursor cell proliferation	IMP	J:180119
Biological Process	GO:0060563	neuroepithelial cell differentiation	IMP	J:180119
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:2000179	positive regulation of neural precursor cell proliferation	IMP	J:180119
Biological Process	GO:0034067	protein localization to Golgi apparatus	ISO	J:164563
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0006898	receptor-mediated endocytosis	ISO	J:164563
Biological Process	GO:0048863	stem cell differentiation	IMP	J:180119