Lrp4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Lrp4
low density lipoprotein receptor-related protein 4
MGI:2442252

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0034185	apolipoprotein binding	ISO	J:155856
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:202742
Molecular Function	GO:0005515	protein binding	IPI	J:205644
Molecular Function	GO:0005515	protein binding	IPI	J:145446
Molecular Function	GO:0005515	protein binding	IPI	J:149003
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:145446
Molecular Function	GO:0030971	receptor tyrosine kinase binding	IPI	J:205644
Molecular Function	GO:0030971	receptor tyrosine kinase binding	IPI	J:145446
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:155856
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031594	neuromuscular junction	IC	J:177552
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:144064
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:202742
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:103781
Cellular Component	GO:0044853	plasma membrane raft	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0097060	synaptic membrane	ISO	J:155856
Biological Process	GO:0150094	amyloid-beta clearance by cellular catabolic process	ISO	J:164563
Biological Process	GO:0048856	anatomical structure development	IMP	J:119654
Biological Process	GO:0048856	anatomical structure development	IMP	J:119654
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0048813	dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:106811
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:119654
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:108168
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:108168
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:106811
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:119654
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:119654
Biological Process	GO:0006897	endocytosis	IEA	J:60000
Biological Process	GO:0048699	generation of neurons	IBA	J:265628
Biological Process	GO:0001942	hair follicle development	IMP	J:119654
Biological Process	GO:0001942	hair follicle development	IMP	J:119654
Biological Process	GO:0001822	kidney development	ISO	J:164563
Biological Process	GO:0001822	kidney development	IMP	J:119654
Biological Process	GO:0001822	kidney development	IMP	J:119654
Biological Process	GO:0060173	limb development	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0050771	negative regulation of axonogenesis	IMP	J:188149
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IDA	J:160170
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IGI	J:160170
Biological Process	GO:0030279	negative regulation of ossification	ISO	J:164563
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:119654
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:119654
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IMP	J:144064
Biological Process	GO:1901631	positive regulation of presynaptic membrane organization	IDA	J:188149
Biological Process	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering	IMP	J:144064
Biological Process	GO:0097104	postsynaptic membrane assembly	IMP	J:177552
Biological Process	GO:0097105	presynaptic membrane assembly	IMP	J:177552
Biological Process	GO:0008104	protein localization	IMP	J:119654
Biological Process	GO:0008104	protein localization	IMP	J:119654
Biological Process	GO:0009954	proximal/distal pattern formation	IMP	J:119654
Biological Process	GO:0043113	receptor clustering	IMP	J:119654
Biological Process	GO:0043113	receptor clustering	IMP	J:119654
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:145446
Biological Process	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	IMP	J:177552
Biological Process	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	IMP	J:188149
Biological Process	GO:0050808	synapse organization	ISO	J:155856
Biological Process	GO:0051124	synaptic assembly at neuromuscular junction	IDA	J:144064
Biological Process	GO:0051124	synaptic assembly at neuromuscular junction	IMP	J:119654
Biological Process	GO:0051124	synaptic assembly at neuromuscular junction	IMP	J:119654
Biological Process	GO:0016055	Wnt signaling pathway	IDA	J:138365
Biological Process	GO:0016055	Wnt signaling pathway	IDA	J:106811

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24