GO Annotations Graph

• Symbol: Spx
• Name: spexin hormone
• ID: MGI:2442262

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005179	hormone activity	IEA	J:60000
Molecular Function	GO:0005184	neuropeptide hormone activity	ISO	J:164563
Molecular Function	GO:0005184	neuropeptide hormone activity	ISO	J:164563
Molecular Function	GO:0005184	neuropeptide hormone activity	ISS	J:241482
Molecular Function	GO:0005184	neuropeptide hormone activity	IBA	J:265628
Molecular Function	GO:0031765	type 2 galanin receptor binding	ISO	J:164563
Molecular Function	GO:0031766	type 3 galanin receptor binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0031045	dense core granule	ISS	J:241482
Cellular Component	GO:0031045	dense core granule	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISS	J:241482
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0044539	long-chain fatty acid import into cell	ISO	J:155856
Biological Process	GO:0044539	long-chain fatty acid import into cell	IDA	J:211316
Biological Process	GO:0032099	negative regulation of appetite	IDA	J:211316
Biological Process	GO:0032099	negative regulation of appetite	ISO	J:155856
Biological Process	GO:0010459	negative regulation of heart rate	ISO	J:155856
Biological Process	GO:0035814	negative regulation of renal sodium excretion	ISO	J:155856
Biological Process	GO:1904306	positive regulation of gastro-intestinal system smooth muscle contraction	ISS	J:241482
Biological Process	GO:1904306	positive regulation of gastro-intestinal system smooth muscle contraction	ISO	J:164563
Biological Process	GO:1904306	positive regulation of gastro-intestinal system smooth muscle contraction	IBA	J:265628
Biological Process	GO:0003084	positive regulation of systemic arterial blood pressure	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0051930	regulation of sensory perception of pain	ISO	J:155856