GO Annotations Graph

• Symbol: Rc3h2
• Name: ring finger and CCCH-type zinc finger domains 2
• ID: MGI:2442789

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003725	double-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003729	mRNA binding	IDA	J:196136
Molecular Function	GO:0005515	protein binding	IPI	J:196136
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0035613	RNA stem-loop binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	IEA	J:72247
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Biological Process	GO:0001782	B cell homeostasis	IGI	J:196136
Biological Process	GO:0060173	limb development	IMP	J:196136
Biological Process	GO:0048286	lung alveolus development	IMP	J:196136
Biological Process	GO:0048535	lymph node development	IGI	J:196136
Biological Process	GO:0035264	multicellular organism growth	IMP	J:196136
Biological Process	GO:2000320	negative regulation of T-helper 17 cell differentiation	IMP	J:259145
Biological Process	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	IBA	J:265628
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	IDA	J:196136
Biological Process	GO:0009791	post-embryonic development	IMP	J:196136
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	IDA	J:196136
Biological Process	GO:0000209	protein polyubiquitination	ISO	J:164563
Biological Process	GO:0016567	protein ubiquitination	IEA	J:72247
Biological Process	GO:0010468	regulation of gene expression	IDA	J:196136
Biological Process	GO:2000628	regulation of miRNA metabolic process	IMP	J:221791
Biological Process	GO:0048536	spleen development	IGI	J:196136
Biological Process	GO:0043029	T cell homeostasis	IGI	J:196136
Biological Process	GO:0042098	T cell proliferation	IGI	J:196136
Biological Process	GO:0050852	T cell receptor signaling pathway	IMP	J:259145
Biological Process	GO:0061470	T follicular helper cell differentiation	IGI	J:196136
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IBA	J:265628