GO Annotations Graph

• Symbol: Mettl14
• Name: methyltransferase 14, N6-adenosine-methyltransferase subunit
• ID: MGI:2442926

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001734	mRNA (N6-adenosine)-methyltransferase activity	IDA	J:207885
Molecular Function	GO:0003729	mRNA binding	ISO	J:164563
Molecular Function	GO:0003729	mRNA binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:207885
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	NAS	J:319950
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:250428
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:207885
Cellular Component	GO:0036396	RNA N6-methyladenosine methyltransferase complex	IDA	J:261823
Cellular Component	GO:0036396	RNA N6-methyladenosine methyltransferase complex	ISO	J:164563
Cellular Component	GO:0036396	RNA N6-methyladenosine methyltransferase complex	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0021861	forebrain radial glial cell differentiation	IMP	J:247703
Biological Process	GO:0042063	gliogenesis	IMP	J:247703
Biological Process	GO:0006402	mRNA catabolic process	IMP	J:247703
Biological Process	GO:0061157	mRNA destabilization	IMP	J:207885
Biological Process	GO:0061157	mRNA destabilization	IMP	J:247703
Biological Process	GO:0080009	mRNA methylation	IDA	J:207885
Biological Process	GO:0080009	mRNA methylation	IDA	J:247703
Biological Process	GO:0080009	mRNA methylation	ISO	J:164563
Biological Process	GO:0080009	mRNA methylation	NAS	J:319950
Biological Process	GO:0080009	mRNA methylation	IBA	J:265628
Biological Process	GO:0080009	mRNA methylation	IMP	J:285490
Biological Process	GO:0000398	mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation	IMP	J:271531
Biological Process	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation	ISO	J:164563
Biological Process	GO:0045727	positive regulation of translation	ISO	J:164563
Biological Process	GO:0045664	regulation of neuron differentiation	IMP	J:285490
Biological Process	GO:0001510	RNA methylation	IMP	J:250428
Biological Process	GO:0007283	spermatogenesis	IMP	J:250428
Biological Process	GO:0019827	stem cell population maintenance	IMP	J:207885