GO Annotations Graph

• Symbol: Rab8b
• Name: RAB8B, member RAS oncogene family
• ID: MGI:2442982

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019003	GDP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0005525	GTP binding	IEA	J:72247
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:200405
Molecular Function	GO:0005515	protein binding	IPI	J:116097
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0030911	TPR domain binding	ISO	J:155856
Cellular Component	GO:0051286	cell tip	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0005768	endosome	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005778	peroxisomal membrane	ISO	J:164563
Cellular Component	GO:0045335	phagocytic vesicle	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	IBA	J:265628
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	IBA	J:265628
Biological Process	GO:0019882	antigen processing and presentation	ISO	J:164563
Biological Process	GO:0150115	cell-substrate junction organization	ISO	J:155856
Biological Process	GO:0048210	Golgi vesicle fusion to target membrane	IBA	J:265628
Biological Process	GO:0031346	positive regulation of cell projection organization	ISO	J:155856
Biological Process	GO:0051461	positive regulation of corticotropin secretion	ISO	J:155856
Biological Process	GO:0045046	protein import into peroxisome membrane	ISO	J:164563
Biological Process	GO:0072659	protein localization to plasma membrane	IBA	J:265628
Biological Process	GO:0009306	protein secretion	IBA	J:265628
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0017157	regulation of exocytosis	IBA	J:265628
Biological Process	GO:0006904	vesicle docking involved in exocytosis	IBA	J:265628