GO Annotations Graph

• Symbol: Tns3
• Name: tensin 3
• ID: MGI:2443012

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005091	guanyl-nucleotide exchange factor adaptor activity	IDA	J:246351
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:246351
Molecular Function	GO:0005515	protein binding	IPI	J:246351
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0002102	podosome	IDA	J:246351
Biological Process	GO:0045453	bone resorption	IMP	J:246351
Biological Process	GO:0008283	cell population proliferation	IMP	J:96666
Biological Process	GO:0008283	cell population proliferation	IMP	J:96666
Biological Process	GO:0016311	dephosphorylation	IEA	J:72247
Biological Process	GO:0043542	endothelial cell migration	IMP	J:96666
Biological Process	GO:0048286	lung alveolus development	IMP	J:96666
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IMP	J:246351
Biological Process	GO:0071800	podosome assembly	IMP	J:246351
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:96666
Biological Process	GO:1905099	positive regulation of guanyl-nucleotide exchange factor activity	IDA	J:246351
Biological Process	GO:0035022	positive regulation of Rac protein signal transduction	IPI	J:246351