GO Annotations Graph

• Symbol: Ttll1
• Name: tubulin tyrosine ligase-like 1
• ID: MGI:2443047

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016874	ligase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:125904
Molecular Function	GO:0015631	tubulin binding	IBA	J:265628
Molecular Function	GO:0070740	tubulin-glutamic acid ligase activity	EXP	J:241131
Molecular Function	GO:0070740	tubulin-glutamic acid ligase activity	ISO	J:164563
Molecular Function	GO:0070740	tubulin-glutamic acid ligase activity	IBA	J:265628
Molecular Function	GO:0070740	tubulin-glutamic acid ligase activity	IDA	J:267916
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0036064	ciliary basal body	IDA	J:130247
Cellular Component	GO:0005929	cilium	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-NUL-8955873
Cellular Component	GO:0005576	extracellular region	IMP	J:263164
Cellular Component	GO:0005874	microtubule	ISO	J:164563
Cellular Component	GO:0031514	motile cilium	IEA	J:60000
Biological Process	GO:0035082	axoneme assembly	IMP	J:161297
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	IGI	J:267916
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	IMP	J:186050
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	IMP	J:161297
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	IMP	J:186050
Biological Process	GO:0030317	flagellated sperm motility	IMP	J:186050
Biological Process	GO:0002395	immune response in nasopharyngeal-associated lymphoid tissue	IMP	J:263164
Biological Process	GO:0002395	immune response in nasopharyngeal-associated lymphoid tissue	IMP	J:263164
Biological Process	GO:0000226	microtubule cytoskeleton organization	ISO	J:164563
Biological Process	GO:0000226	microtubule cytoskeleton organization	IBA	J:265628
Biological Process	GO:0120197	mucociliary clearance	IMP	J:263164
Biological Process	GO:0120197	mucociliary clearance	IMP	J:263164
Biological Process	GO:0036211	protein modification process	IEA	J:72247
Biological Process	GO:0018095	protein polyglutamylation	TAS	Reactome:R-NUL-8955873
Biological Process	GO:0018095	protein polyglutamylation	IBA	J:265628
Biological Process	GO:0018095	protein polyglutamylation	IDA	J:259707
Biological Process	GO:0018095	protein polyglutamylation	IMP	J:259707
Biological Process	GO:0018095	protein polyglutamylation	IDA	J:267916
Biological Process	GO:0018095	protein polyglutamylation	IMP	J:161297
Biological Process	GO:0120222	regulation of blastocyst development	IMP	J:259707
Biological Process	GO:0007288	sperm axoneme assembly	IMP	J:161297
Biological Process	GO:0007288	sperm axoneme assembly	IMP	J:186050