GO Annotations Graph

• Symbol: Mib1
• Name: MIB E3 ubiquitin protein ligase 1
• ID: MGI:2443157

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:201307
Molecular Function	GO:0005515	protein binding	IPI	J:180704
Molecular Function	GO:0005515	protein binding	IPI	J:101173
Molecular Function	GO:0005515	protein binding	IPI	J:101173
Molecular Function	GO:0005515	protein binding	IPI	J:101173
Molecular Function	GO:0005515	protein binding	IPI	J:101173
Molecular Function	GO:0005515	protein binding	IPI	J:101173
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	IEA	J:72247
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:101173
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Biological Process	GO:0001568	blood vessel development	IMP	J:101173
Biological Process	GO:0001568	blood vessel development	IMP	J:101173
Biological Process	GO:0006897	endocytosis	IBA	J:265628
Biological Process	GO:0007507	heart development	IMP	J:101173
Biological Process	GO:0001947	heart looping	IMP	J:101173
Biological Process	GO:0001701	in utero embryonic development	IMP	J:101173
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:101173
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:101173
Biological Process	GO:0001841	neural tube formation	IMP	J:101173
Biological Process	GO:0030182	neuron differentiation	IMP	J:101173
Biological Process	GO:0007219	Notch signaling pathway	IBA	J:265628
Biological Process	GO:0007219	Notch signaling pathway	IMP	J:101173
Biological Process	GO:0045807	positive regulation of endocytosis	IDA	J:101173
Biological Process	GO:0016567	protein ubiquitination	IBA	J:265628
Biological Process	GO:0001756	somitogenesis	IMP	J:101173
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	ISO	J:164563