GO Annotations Graph

• Symbol: Pde12
• Name: phosphodiesterase 12
• ID: MGI:2443226

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	ISO	J:164563
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	IBA	J:265628
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0004527	exonuclease activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004518	nuclease activity	IEA	J:60000
Molecular Function	GO:0004535	poly(A)-specific ribonuclease activity	ISO	J:164563
Cellular Component	GO:0005759	mitochondrial matrix	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Biological Process	GO:0071359	cellular response to dsRNA	ISO	J:164563
Biological Process	GO:0035457	cellular response to interferon-alpha	ISO	J:164563
Biological Process	GO:0071346	cellular response to type II interferon	ISO	J:164563
Biological Process	GO:0000958	mitochondrial mRNA catabolic process	ISO	J:164563
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:164563
Biological Process	GO:0090324	negative regulation of oxidative phosphorylation	ISO	J:164563
Biological Process	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	ISO	J:164563
Biological Process	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	IBA	J:265628
Biological Process	GO:0090305	nucleic acid phosphodiester bond hydrolysis	ISO	J:164563
Biological Process	GO:0045070	positive regulation of viral genome replication	ISO	J:164563
Biological Process	GO:0044528	regulation of mitochondrial mRNA stability	ISO	J:164563
Biological Process	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	ISO	J:164563