GO Annotations Graph

• Symbol: Ndufs1
• Name: NADH:ubiquinone oxidoreductase core subunit S1
• ID: MGI:2443241

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051537	2 iron, 2 sulfur cluster binding	IEA	J:60000
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	IEA	J:60000
Molecular Function	GO:0009055	electron transfer activity	IMP	J:297322
Molecular Function	GO:0051536	iron-sulfur cluster binding	IEA	J:60000
Molecular Function	GO:0051536	iron-sulfur cluster binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	ISO	J:164563
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	IMP	J:297322
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	IMP	J:289389
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	ISO	J:164563
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016651	oxidoreductase activity, acting on NAD(P)H	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:289389
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	IEA	J:60000
Cellular Component	GO:0005758	mitochondrial intermembrane space	ISO	J:164563
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:289389
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0070469	respirasome	IEA	J:60000
Biological Process	GO:0009060	aerobic respiration	NAS	J:320063
Biological Process	GO:0008637	apoptotic mitochondrial changes	ISO	J:164563
Biological Process	GO:0046034	ATP metabolic process	ISO	J:164563
Biological Process	GO:0042773	ATP synthesis coupled electron transport	IEA	J:72247
Biological Process	GO:0045333	cellular respiration	ISO	J:164563
Biological Process	GO:0006120	mitochondrial electron transport, NADH to ubiquinone	ISO	J:164563
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	ISO	J:164563
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	IMP	J:297322
Biological Process	GO:0042776	proton motive force-driven mitochondrial ATP synthesis	NAS	J:320063
Biological Process	GO:0072593	reactive oxygen species metabolic process	ISO	J:164563
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	ISO	J:164563