GO Annotations Graph

• Symbol: Mcph1
• Name: microcephaly, primary autosomal recessive 1
• ID: MGI:2443308

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Biological Process	GO:0060348	bone development	IMP	J:199385
Biological Process	GO:0021987	cerebral cortex development	IMP	J:180706
Biological Process	GO:0000132	establishment of mitotic spindle orientation	IMP	J:180706
Biological Process	GO:0000278	mitotic cell cycle	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0097150	neuronal stem cell population maintenance	IMP	J:180706
Biological Process	GO:0071539	protein localization to centrosome	IMP	J:180706
Biological Process	GO:0046605	regulation of centrosome cycle	IMP	J:180706
Biological Process	GO:0060623	regulation of chromosome condensation	IMP	J:157993
Biological Process	GO:0010468	regulation of gene expression	IMP	J:176173
Biological Process	GO:0010468	regulation of gene expression	IGI	J:176173
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:199385
Biological Process	GO:0043549	regulation of kinase activity	IMP	J:176173