GO Annotations Graph

• Symbol: Dgki
• Name: diacylglycerol kinase, iota
• ID: MGI:2443430

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0004143	diacylglycerol kinase activity	ISO	J:164563
Molecular Function	GO:0004143	diacylglycerol kinase activity	ISO	J:155856
Molecular Function	GO:0004143	diacylglycerol kinase activity	IBA	J:265628
Molecular Function	GO:0004143	diacylglycerol kinase activity	IDA	J:99817
Molecular Function	GO:0005095	GTPase inhibitor activity	IDA	J:99817
Molecular Function	GO:0005095	GTPase inhibitor activity	IMP	J:99817
Molecular Function	GO:0016301	kinase activity	IEA	J:72247
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003951	NAD+ kinase activity	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0031267	small GTPase binding	IPI	J:99817
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0043679	axon terminus	ISO	J:168713
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:99817
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:168713
Cellular Component	GO:0043197	dendritic spine	ISO	J:168713
Cellular Component	GO:0060076	excitatory synapse	ISO	J:168713
Cellular Component	GO:0099147	extrinsic component of postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0098891	extrinsic component of presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:168713
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:168713
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	IDA	J:99817
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:168713
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:99817
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0014069	postsynaptic density	ISO	J:168713
Cellular Component	GO:0098793	presynapse	IDA	J:168713
Cellular Component	GO:0048786	presynaptic active zone	ISO	J:168713
Cellular Component	GO:0032991	protein-containing complex	ISO	J:168713
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:168713
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:168713
Cellular Component	GO:0045202	synapse	ISO	J:168713
Cellular Component	GO:0097060	synaptic membrane	ISO	J:168713
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:168713
Biological Process	GO:0046339	diacylglycerol metabolic process	ISO	J:155856
Biological Process	GO:0046339	diacylglycerol metabolic process	IBA	J:265628
Biological Process	GO:0060079	excitatory postsynaptic potential	IMP	J:168713
Biological Process	GO:0046959	habituation	IMP	J:168713
Biological Process	GO:0035556	intracellular signal transduction	IBA	J:265628
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0046834	lipid phosphorylation	ISO	J:164563
Biological Process	GO:0046834	lipid phosphorylation	ISO	J:155856
Biological Process	GO:0046834	lipid phosphorylation	IBA	J:265628
Biological Process	GO:0007269	neurotransmitter secretion	IMP	J:168713
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	ISO	J:155856
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	IMP	J:99817
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:168713
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:168713
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:168713
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:168713
Biological Process	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007265	Ras protein signal transduction	IMP	J:99817
Biological Process	GO:0043087	regulation of GTPase activity	IMP	J:99817
Biological Process	GO:1900452	regulation of long-term synaptic depression	IMP	J:168713
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	IBA	J:265628
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	IMP	J:168713
Biological Process	GO:0007165	signal transduction	IEA	J:72247