GO Annotations Graph

• Symbol: Abat
• Name: 4-aminobutyrate aminotransferase
• ID: MGI:2443582

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047298	(S)-3-amino-2-methylpropionate transaminase activity	IEA	J:72245
Molecular Function	GO:0003867	4-aminobutyrate transaminase activity	ISO	J:164563
Molecular Function	GO:0003867	4-aminobutyrate transaminase activity	ISO	J:155856
Molecular Function	GO:0003867	4-aminobutyrate transaminase activity	IBA	J:265628
Molecular Function	GO:0034386	4-aminobutyrate:2-oxoglutarate transaminase activity	IEA	J:72245
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0051536	iron-sulfur cluster binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0030170	pyridoxal phosphate binding	ISO	J:164563
Molecular Function	GO:0030170	pyridoxal phosphate binding	IBA	J:265628
Molecular Function	GO:0008483	transaminase activity	IEA	J:60000
Molecular Function	GO:0008483	transaminase activity	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0032144	4-aminobutyrate transaminase complex	ISO	J:164563
Cellular Component	GO:0005759	mitochondrial matrix	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Biological Process	GO:0007568	aging	ISO	J:155856
Biological Process	GO:0048148	behavioral response to cocaine	IMP	J:115381
Biological Process	GO:0007620	copulation	ISO	J:155856
Biological Process	GO:0035640	exploration behavior	ISO	J:155856
Biological Process	GO:0009449	gamma-aminobutyric acid biosynthetic process	ISO	J:155856
Biological Process	GO:0009450	gamma-aminobutyric acid catabolic process	IBA	J:265628
Biological Process	GO:0009448	gamma-aminobutyric acid metabolic process	ISO	J:164563
Biological Process	GO:0007626	locomotory behavior	ISO	J:155856
Biological Process	GO:0045776	negative regulation of blood pressure	ISO	J:155856
Biological Process	GO:0033602	negative regulation of dopamine secretion	ISO	J:155856
Biological Process	GO:0014053	negative regulation of gamma-aminobutyric acid secretion	ISO	J:155856
Biological Process	GO:0090331	negative regulation of platelet aggregation	ISO	J:155856
Biological Process	GO:0042135	neurotransmitter catabolic process	IEA	J:60000
Biological Process	GO:1904450	positive regulation of aspartate secretion	ISO	J:155856
Biological Process	GO:0045964	positive regulation of dopamine metabolic process	ISO	J:155856
Biological Process	GO:0031652	positive regulation of heat generation	ISO	J:155856
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	ISO	J:155856
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:155856
Biological Process	GO:1902722	positive regulation of prolactin secretion	ISO	J:155856
Biological Process	GO:0070474	positive regulation of uterine smooth muscle contraction	ISO	J:155856
Biological Process	GO:0042220	response to cocaine	ISO	J:155856
Biological Process	GO:0045471	response to ethanol	ISO	J:155856
Biological Process	GO:0001666	response to hypoxia	ISO	J:155856
Biological Process	GO:0010039	response to iron ion	ISO	J:155856
Biological Process	GO:0035094	response to nicotine	ISO	J:155856
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856