GO Annotations Graph

• Symbol: Fermt1
• Name: fermitin family member 1
• ID: MGI:2443583

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051015	actin filament binding	IDA	J:114381
Molecular Function	GO:0051015	actin filament binding	IDA	J:114381
Molecular Function	GO:0005178	integrin binding	IBA	J:265628
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0071944	cell periphery	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	IBA	J:265628
Cellular Component	GO:0005925	focal adhesion	IDA	J:114381
Cellular Component	GO:0005925	focal adhesion	IDA	J:114381
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0071711	basement membrane organization	IMP	J:210448
Biological Process	GO:0007155	cell adhesion	ISO	J:164563
Biological Process	GO:0007160	cell-matrix adhesion	IBA	J:265628
Biological Process	GO:0090162	establishment of epithelial cell polarity	ISO	J:164563
Biological Process	GO:0007229	integrin-mediated signaling pathway	IEA	J:72247
Biological Process	GO:0051546	keratinocyte migration	ISO	J:164563
Biological Process	GO:0043616	keratinocyte proliferation	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IMP	J:210448
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:210448
Biological Process	GO:0042308	negative regulation of protein import into nucleus	IMP	J:210448
Biological Process	GO:2000647	negative regulation of stem cell proliferation	IMP	J:210448
Biological Process	GO:0051886	negative regulation of timing of anagen	IMP	J:210448
Biological Process	GO:0033630	positive regulation of cell adhesion mediated by integrin	IMP	J:210448
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	IMP	J:210448
Biological Process	GO:0033625	positive regulation of integrin activation	ISO	J:164563
Biological Process	GO:0071636	positive regulation of transforming growth factor beta production	IMP	J:210448
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	IMP	J:210448
Biological Process	GO:1903691	positive regulation of wound healing, spreading of epidermal cells	ISO	J:164563