GO Annotations Graph

• Symbol: Numa1
• Name: nuclear mitotic apparatus protein 1
• ID: MGI:2443665

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0097718	disordered domain specific binding	ISO	J:164563
Molecular Function	GO:0070840	dynein complex binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0008017	microtubule binding	ISO	J:164563
Molecular Function	GO:0008017	microtubule binding	ISO	J:155856
Molecular Function	GO:0008017	microtubule binding	IBA	J:265628
Molecular Function	GO:0051011	microtubule minus-end binding	ISO	J:164563
Molecular Function	GO:0051010	microtubule plus-end binding	ISO	J:164563
Molecular Function	GO:0035091	phosphatidylinositol binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:306588
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0015631	tubulin binding	ISO	J:164563
Molecular Function	GO:0015631	tubulin binding	ISO	J:73065
Cellular Component	GO:0045177	apical part of cell	IDA	J:171504
Cellular Component	GO:0045177	apical part of cell	IDA	J:171504
Cellular Component	GO:0045177	apical part of cell	IDA	J:171504
Cellular Component	GO:0045177	apical part of cell	IDA	J:171504
Cellular Component	GO:0005938	cell cortex	ISO	J:164563
Cellular Component	GO:0099738	cell cortex region	ISO	J:164563
Cellular Component	GO:0099738	cell cortex region	IDA	J:229900
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005813	centrosome	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0055028	cortical microtubule	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:1905720	cytoplasmic microtubule bundle	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0019897	extrinsic component of plasma membrane	ISO	J:164563
Cellular Component	GO:0000139	Golgi membrane	IEA	J:72247
Cellular Component	GO:0097575	lateral cell cortex	IMP	J:239972
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005874	microtubule	IEA	J:60000
Cellular Component	GO:0097427	microtubule bundle	ISO	J:164563
Cellular Component	GO:0036449	microtubule minus-end	ISO	J:164563
Cellular Component	GO:0035371	microtubule plus-end	ISO	J:164563
Cellular Component	GO:0072686	mitotic spindle	ISO	J:164563
Cellular Component	GO:0061673	mitotic spindle astral microtubule	ISO	J:164563
Cellular Component	GO:1990023	mitotic spindle midzone	ISO	J:164563
Cellular Component	GO:0097431	mitotic spindle pole	IDA	J:229900
Cellular Component	GO:0097431	mitotic spindle pole	ISO	J:164563
Cellular Component	GO:0097431	mitotic spindle pole	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0016363	nuclear matrix	ISO	J:164563
Cellular Component	GO:0016363	nuclear matrix	ISO	J:155856
Cellular Component	GO:0016363	nuclear matrix	IDA	J:106641
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0005876	spindle microtubule	ISO	J:164563
Cellular Component	GO:0005876	spindle microtubule	ISO	J:155856
Cellular Component	GO:0005876	spindle microtubule	IBA	J:265628
Cellular Component	GO:0000922	spindle pole	ISO	J:155856
Cellular Component	GO:0000922	spindle pole	ISO	J:164563
Cellular Component	GO:0000922	spindle pole	IBA	J:265628
Cellular Component	GO:0000922	spindle pole	ISO	J:204810
Cellular Component	GO:0031616	spindle pole centrosome	ISO	J:164563
Biological Process	GO:0055048	anastral spindle assembly	ISO	J:164563
Biological Process	GO:0030953	astral microtubule organization	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0007059	chromosome segregation	IEA	J:60000
Biological Process	GO:0000132	establishment of mitotic spindle orientation	IMP	J:229900
Biological Process	GO:0000132	establishment of mitotic spindle orientation	ISO	J:164563
Biological Process	GO:0000132	establishment of mitotic spindle orientation	IBA	J:265628
Biological Process	GO:0000132	establishment of mitotic spindle orientation	IMP	J:171504
Biological Process	GO:0060487	lung epithelial cell differentiation	IMP	J:171504
Biological Process	GO:0001578	microtubule bundle formation	ISO	J:164563
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	IMP	J:229900
Biological Process	GO:0051984	positive regulation of chromosome segregation	ISO	J:164563
Biological Process	GO:1905820	positive regulation of chromosome separation	ISO	J:164563
Biological Process	GO:0051798	positive regulation of hair follicle development	IMP	J:229900
Biological Process	GO:0032388	positive regulation of intracellular transport	ISO	J:164563
Biological Process	GO:0045618	positive regulation of keratinocyte differentiation	IMP	J:229900
Biological Process	GO:0031116	positive regulation of microtubule polymerization	ISO	J:164563
Biological Process	GO:1902846	positive regulation of mitotic spindle elongation	ISO	J:164563
Biological Process	GO:1904778	positive regulation of protein localization to cell cortex	ISO	J:164563
Biological Process	GO:1902365	positive regulation of protein localization to spindle pole body	ISO	J:164563
Biological Process	GO:1905832	positive regulation of spindle assembly	ISO	J:164563
Biological Process	GO:0090235	regulation of metaphase plate congression	ISO	J:164563
Biological Process	GO:0060236	regulation of mitotic spindle organization	ISO	J:164563