GO Annotations Graph

• Symbol: Sipa1l1
• Name: signal-induced proliferation-associated 1 like 1
• ID: MGI:2443679

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051015	actin filament binding	ISO	J:155856
Molecular Function	GO:0046875	ephrin receptor binding	IPI	J:130934
Molecular Function	GO:0005096	GTPase activator activity	IBA	J:265628
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:155856
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0031532	actin cytoskeleton reorganization	ISO	J:155856
Biological Process	GO:0090630	activation of GTPase activity	ISO	J:155856
Biological Process	GO:0090630	activation of GTPase activity	IBA	J:265628
Biological Process	GO:0048013	ephrin receptor signaling pathway	IMP	J:130934
Biological Process	GO:0048013	ephrin receptor signaling pathway	IMP	J:128698
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	ISO	J:155856
Biological Process	GO:0050770	regulation of axonogenesis	IDA	J:130934
Biological Process	GO:0048814	regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	ISO	J:155856
Biological Process	GO:0043087	regulation of GTPase activity	ISO	J:155856
Biological Process	GO:0043087	regulation of GTPase activity	IMP	J:130934
Biological Process	GO:0099151	regulation of postsynaptic density assembly	ISO	J:155856
Biological Process	GO:0051056	regulation of small GTPase mediated signal transduction	IEA	J:72247
Biological Process	GO:0048167	regulation of synaptic plasticity	ISO	J:155856