GO Annotations Graph

• Symbol: Spef2
• Name: sperm flagellar 2
• ID: MGI:2443727

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:159553
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005929	cilium	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:159553
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:159553
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:159553
Cellular Component	GO:0002177	manchette	IBA	J:265628
Cellular Component	GO:0002177	manchette	IDA	J:159553
Cellular Component	GO:0031514	motile cilium	IEA	J:60000
Cellular Component	GO:0036126	sperm flagellum	ISO	J:164563
Cellular Component	GO:0097225	sperm midpiece	IBA	J:265628
Cellular Component	GO:0097225	sperm midpiece	IDA	J:159553
Biological Process	GO:0048854	brain morphogenesis	IMP	J:176695
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0090660	cerebrospinal fluid circulation	IGI	J:294202
Biological Process	GO:0090660	cerebrospinal fluid circulation	IGI	J:294202
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	IMP	J:176695
Biological Process	GO:0051649	establishment of localization in cell	IGI	J:294202
Biological Process	GO:0051649	establishment of localization in cell	IGI	J:294202
Biological Process	GO:0120197	mucociliary clearance	IGI	J:294202
Biological Process	GO:0120197	mucociliary clearance	IGI	J:294202
Biological Process	GO:0120197	mucociliary clearance	IGI	J:294202
Biological Process	GO:0120197	mucociliary clearance	IGI	J:294202
Biological Process	GO:0120197	mucociliary clearance	IMP	J:206387
Biological Process	GO:0060541	respiratory system development	IMP	J:176695
Biological Process	GO:0048705	skeletal system morphogenesis	IMP	J:176695
Biological Process	GO:0007288	sperm axoneme assembly	ISO	J:164563
Biological Process	GO:0007288	sperm axoneme assembly	IBA	J:265628
Biological Process	GO:0007288	sperm axoneme assembly	IMP	J:176695
Biological Process	GO:0120316	sperm flagellum assembly	IGI	J:294202
Biological Process	GO:0007283	spermatogenesis	IMP	J:176695