GO Annotations Graph

• Symbol: Mat2a
• Name: methionine adenosyltransferase 2A
• ID: MGI:2443731

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016597	amino acid binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004478	methionine adenosyltransferase activity	ISO	J:164563
Molecular Function	GO:0004478	methionine adenosyltransferase activity	ISO	J:155856
Molecular Function	GO:0004478	methionine adenosyltransferase activity	IBA	J:265628
Molecular Function	GO:0004478	methionine adenosyltransferase activity	IDA	J:78144
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0036094	small molecule binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0048269	methionine adenosyltransferase complex	ISO	J:164563
Cellular Component	GO:0048269	methionine adenosyltransferase complex	IBA	J:265628
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0007623	circadian rhythm	ISO	J:155856
Biological Process	GO:0006730	one-carbon metabolic process	IEA	J:60000
Biological Process	GO:0051291	protein heterooligomerization	ISO	J:164563
Biological Process	GO:0034214	protein hexamerization	ISO	J:164563
Biological Process	GO:0051591	response to cAMP	ISO	J:155856
Biological Process	GO:0009725	response to hormone	ISO	J:155856
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0006556	S-adenosylmethionine biosynthetic process	ISO	J:155856
Biological Process	GO:0006556	S-adenosylmethionine biosynthetic process	ISO	J:164563
Biological Process	GO:0006556	S-adenosylmethionine biosynthetic process	IBA	J:265628
Biological Process	GO:0006556	S-adenosylmethionine biosynthetic process	IDA	J:78144