GO Annotations Graph

• Symbol: Pde8b
• Name: phosphodiesterase 8B
• ID: MGI:2443999

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	ISO	J:164563
Molecular Function	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	IBA	J:265628
Molecular Function	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	IDA	J:203335
Molecular Function	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008081	phosphoric diester hydrolase activity	IEA	J:72247
Biological Process	GO:0001662	behavioral fear response	IMP	J:203250
Biological Process	GO:0046676	negative regulation of insulin secretion	ISO	J:155856
Biological Process	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:0090032	negative regulation of steroid hormone biosynthetic process	IMP	J:203335
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:203250
Biological Process	GO:0035106	operant conditioning	IMP	J:203250
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0008542	visual learning	IMP	J:203250