GO Annotations Graph

• Symbol: Ccar2
• Name: cell cycle activator and apoptosis regulator 2
• ID: MGI:2444228

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0004857	enzyme inhibitor activity	IDA	J:149260
Molecular Function	GO:0004857	enzyme inhibitor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:198046
Molecular Function	GO:0000993	RNA polymerase II complex binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0044609	DBIRD complex	ISO	J:164563
Cellular Component	GO:0005759	mitochondrial matrix	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005819	spindle	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	ISO	J:164563
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0043086	negative regulation of catalytic activity	ISO	J:164563
Biological Process	GO:0043086	negative regulation of catalytic activity	IMP	J:221556
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	ISO	J:164563
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:2000003	positive regulation of DNA damage checkpoint	ISO	J:164563
Biological Process	GO:0042752	regulation of circadian rhythm	IMP	J:198046
Biological Process	GO:0006355	regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0032784	regulation of DNA-templated transcription elongation	ISO	J:164563
Biological Process	GO:0090311	regulation of protein deacetylation	ISO	J:164563
Biological Process	GO:0031647	regulation of protein stability	ISO	J:164563
Biological Process	GO:0009411	response to UV	ISO	J:164563
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0008380	RNA splicing	ISO	J:164563
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000