GO Annotations Graph

• Symbol: Coro2b
• Name: coronin, actin binding protein, 2B
• ID: MGI:2444283

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:1990147	talin binding	ISO	J:254431
Molecular Function	GO:0017166	vinculin binding	ISO	J:254431
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005925	focal adhesion	IDA	J:254431
Cellular Component	GO:0005925	focal adhesion	ISO	J:254431
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0001725	stress fiber	ISO	J:254431
Biological Process	GO:0030036	actin cytoskeleton organization	IEA	J:72247
Biological Process	GO:0048041	focal adhesion assembly	IMP	J:254431
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	ISO	J:254431
Biological Process	GO:1904950	negative regulation of establishment of protein localization	ISO	J:254431
Biological Process	GO:0051497	negative regulation of stress fiber assembly	IMP	J:254431
Biological Process	GO:1904951	positive regulation of establishment of protein localization	ISO	J:254431
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:254431
Biological Process	GO:0080135	regulation of cellular response to stress	ISO	J:254431
Biological Process	GO:0003093	regulation of glomerular filtration	IMP	J:254431