GO Annotations Graph

• Symbol: Frem2
• Name: Fras1 related extracellular matrix protein 2
• ID: MGI:2444465

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:111788
Cellular Component	GO:0005604	basement membrane	IDA	J:117883
Cellular Component	GO:0005604	basement membrane	IDA	J:111788
Cellular Component	GO:0005604	basement membrane	IDA	J:128304
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0009653	anatomical structure morphogenesis	IBA	J:265628
Biological Process	GO:0007155	cell adhesion	ISO	J:164563
Biological Process	GO:0007154	cell communication	IEA	J:72247
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:223062
Biological Process	GO:0001654	eye development	ISO	J:164563
Biological Process	GO:0001654	eye development	IMP	J:279933
Biological Process	GO:0001654	eye development	IMP	J:223062
Biological Process	GO:0007507	heart development	IMP	J:222159
Biological Process	GO:0048839	inner ear development	IDA	J:174607
Biological Process	GO:0001822	kidney development	IMP	J:231949
Biological Process	GO:0002009	morphogenesis of an epithelium	IMP	J:98344
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000