GO Annotations Graph

• Symbol: Mapkap1
• Name: mitogen-activated protein kinase associated protein 1
• ID: MGI:2444554

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0070300	phosphatidic acid binding	ISO	J:164563
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	ISO	J:164563
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:167176
Molecular Function	GO:0005515	protein binding	IPI	J:172256
Molecular Function	GO:0005515	protein binding	IPI	J:172256
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0031932	TORC2 complex	IDA	J:125618
Cellular Component	GO:0031932	TORC2 complex	ISO	J:164563
Cellular Component	GO:0031932	TORC2 complex	IBA	J:265628
Biological Process	GO:0031669	cellular response to nutrient levels	NAS	J:319697
Biological Process	GO:0007010	cytoskeleton organization	NAS	J:320275
Biological Process	GO:0043066	negative regulation of apoptotic process	NAS	J:319697
Biological Process	GO:0046580	negative regulation of Ras protein signal transduction	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	ISO	J:164563
Biological Process	GO:0030307	positive regulation of cell growth	NAS	J:319697
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	IMP	J:125618
Biological Process	GO:1900407	regulation of cellular response to oxidative stress	IMP	J:125618
Biological Process	GO:0038203	TORC2 signaling	IBA	J:265628