GO Annotations Graph

• Symbol: Nlgn3
• Name: neuroligin 3
• ID: MGI:2444609

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:155856
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0042043	neurexin family protein binding	ISO	J:155856
Molecular Function	GO:0042043	neurexin family protein binding	IBA	J:265628
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:164563
Molecular Function	GO:0038023	signaling receptor activity	ISO	J:155856
Molecular Function	GO:0038023	signaling receptor activity	IBA	J:265628
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030139	endocytic vesicle	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	ISO	J:164563
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0060077	inhibitory synapse	ISO	J:155856
Cellular Component	GO:0060077	inhibitory synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0045202	synapse	ISO	J:96464
Biological Process	GO:0030534	adult behavior	ISO	J:164563
Biological Process	GO:0048675	axon extension	ISO	J:155856
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0042745	circadian sleep/wake cycle	ISO	J:155856
Biological Process	GO:0060079	excitatory postsynaptic potential	IMP	J:175606
Biological Process	GO:0060080	inhibitory postsynaptic potential	IMP	J:175606
Biological Process	GO:0060080	inhibitory postsynaptic potential	ISO	J:155856
Biological Process	GO:0060080	inhibitory postsynaptic potential	IMP	J:175606
Biological Process	GO:0060080	inhibitory postsynaptic potential	IMP	J:125344
Biological Process	GO:0007612	learning	ISO	J:164563
Biological Process	GO:0060291	long-term synaptic potentiation	IMP	J:175606
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IGI	J:113647
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IGI	J:113647
Biological Process	GO:0061002	negative regulation of dendritic spine morphogenesis	IMP	J:175606
Biological Process	GO:0090394	negative regulation of excitatory postsynaptic potential	IMP	J:175606
Biological Process	GO:0007158	neuron cell-cell adhesion	ISO	J:155856
Biological Process	GO:0007158	neuron cell-cell adhesion	IBA	J:265628
Biological Process	GO:0048709	oligodendrocyte differentiation	IMP	J:145866
Biological Process	GO:2000969	positive regulation of AMPA receptor activity	IMP	J:184114
Biological Process	GO:0060999	positive regulation of dendritic spine development	ISO	J:155856
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	IMP	J:184114
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	ISO	J:155856
Biological Process	GO:1902474	positive regulation of protein localization to synapse	ISO	J:155856
Biological Process	GO:0051965	positive regulation of synapse assembly	IMP	J:184114
Biological Process	GO:0051965	positive regulation of synapse assembly	ISO	J:155856
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	IMP	J:184114
Biological Process	GO:2000809	positive regulation of synaptic vesicle clustering	IMP	J:175606
Biological Process	GO:0097104	postsynaptic membrane assembly	IMP	J:184114
Biological Process	GO:0097104	postsynaptic membrane assembly	IBA	J:265628
Biological Process	GO:0098698	postsynaptic specialization assembly	ISO	J:155856
Biological Process	GO:0060134	prepulse inhibition	ISO	J:155856
Biological Process	GO:0097105	presynaptic membrane assembly	ISO	J:155856
Biological Process	GO:0097105	presynaptic membrane assembly	IBA	J:265628
Biological Process	GO:0006898	receptor-mediated endocytosis	ISO	J:155856
Biological Process	GO:2000311	regulation of AMPA receptor activity	IMP	J:175606
Biological Process	GO:2000311	regulation of AMPA receptor activity	IMP	J:175606
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	IMP	J:175606
Biological Process	GO:1900271	regulation of long-term synaptic potentiation	IMP	J:175606
Biological Process	GO:2000310	regulation of NMDA receptor activity	IMP	J:175606
Biological Process	GO:2000310	regulation of NMDA receptor activity	IMP	J:175606
Biological Process	GO:0002087	regulation of respiratory gaseous exchange by nervous system process	IGI	J:113647
Biological Process	GO:0002087	regulation of respiratory gaseous exchange by nervous system process	IGI	J:113647
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	IMP	J:175606
Biological Process	GO:2000331	regulation of terminal button organization	IMP	J:175606
Biological Process	GO:2000331	regulation of terminal button organization	IMP	J:175606
Biological Process	GO:0060024	rhythmic synaptic transmission	ISO	J:155856
Biological Process	GO:0035176	social behavior	ISO	J:164563
Biological Process	GO:0035176	social behavior	IMP	J:175606
Biological Process	GO:0035176	social behavior	IMP	J:125344
Biological Process	GO:0007416	synapse assembly	ISO	J:155856
Biological Process	GO:0050808	synapse organization	ISO	J:164563
Biological Process	GO:0050808	synapse organization	IGI	J:176974
Biological Process	GO:0050808	synapse organization	IGI	J:176974
Biological Process	GO:0050808	synapse organization	ISO	J:96464
Biological Process	GO:0050808	synapse organization	IGI	J:176974
Biological Process	GO:0048488	synaptic vesicle endocytosis	IBA	J:265628
Biological Process	GO:0008542	visual learning	IMP	J:125344
Biological Process	GO:0071625	vocalization behavior	ISO	J:164563