GO Annotations Graph

• Symbol: Sh3rf2
• Name: SH3 domain containing ring finger 2
• ID: MGI:2444628

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0019902	phosphatase binding	ISO	J:164563
Molecular Function	GO:0008157	protein phosphatase 1 binding	ISO	J:164563
Molecular Function	GO:0008157	protein phosphatase 1 binding	IBA	J:265628
Molecular Function	GO:0004864	protein phosphatase inhibitor activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IBA	J:265628
Biological Process	GO:0046329	negative regulation of JNK cascade	ISO	J:155856
Biological Process	GO:0031397	negative regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0046330	positive regulation of JNK cascade	ISO	J:164563
Biological Process	GO:0046330	positive regulation of JNK cascade	IBA	J:265628
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	ISO	J:155856
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0051865	protein autoubiquitination	ISO	J:164563
Biological Process	GO:0016567	protein ubiquitination	IBA	J:265628
Biological Process	GO:0046328	regulation of JNK cascade	IEA	J:72247