GO Annotations Graph

• Symbol: Micall2
• Name: MICAL-like 2
• ID: MGI:2444818

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051015	actin filament binding	IDA	J:201396
Molecular Function	GO:0051015	actin filament binding	IDA	J:136002
Molecular Function	GO:0042805	actinin binding	IPI	J:201396
Molecular Function	GO:0031005	filamin binding	ISO	J:164563
Molecular Function	GO:0031005	filamin binding	IDA	J:201396
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:136002
Molecular Function	GO:0005515	protein binding	IPI	J:112525
Molecular Function	GO:0005515	protein binding	IPI	J:136002
Molecular Function	GO:0031267	small GTPase binding	IPI	J:200405
Molecular Function	GO:0031267	small GTPase binding	IPI	J:200405
Molecular Function	GO:0031267	small GTPase binding	IPI	J:200380
Cellular Component	GO:0032432	actin filament bundle	IDA	J:112525
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:112525
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:136002
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:200405
Cellular Component	GO:0055037	recycling endosome	IDA	J:200405
Cellular Component	GO:0001725	stress fiber	IDA	J:201396
Biological Process	GO:0031532	actin cytoskeleton reorganization	IMP	J:201396
Biological Process	GO:0030041	actin filament polymerization	ISO	J:155856
Biological Process	GO:0030041	actin filament polymerization	IMP	J:200380
Biological Process	GO:0070830	bicellular tight junction assembly	IMP	J:200405
Biological Process	GO:0032456	endocytic recycling	IMP	J:200405
Biological Process	GO:0032456	endocytic recycling	IDA	J:112525
Biological Process	GO:0031175	neuron projection development	IMP	J:200380
Biological Process	GO:0031175	neuron projection development	ISO	J:155856
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	IMP	J:201396