GO Annotations Graph

• Symbol: Ripor2
• Name: RHO family interacting cell polarization regulator 2
• ID: MGI:2444879

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	ISO	J:164563
Molecular Function	GO:0071889	14-3-3 protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IMP	J:234083
Molecular Function	GO:0005515	protein binding	IPI	J:234083
Molecular Function	GO:0005515	protein binding	IPI	J:215951
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:73065
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9659536
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9663360
Cellular Component	GO:0030175	filopodium	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0032420	stereocilium	IDA	J:234083
Cellular Component	GO:0032420	stereocilium	ISO	J:155856
Cellular Component	GO:0060171	stereocilium membrane	ISO	J:73065
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	IMP	J:234083
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:1990869	cellular response to chemokine	ISO	J:164563
Biological Process	GO:1990869	cellular response to chemokine	IMP	J:240585
Biological Process	GO:0071260	cellular response to mechanical stimulus	IMP	J:234083
Biological Process	GO:0006935	chemotaxis	IEA	J:60000
Biological Process	GO:0045184	establishment of protein localization	IMP	J:234083
Biological Process	GO:0007517	muscle organ development	IEA	J:60000
Biological Process	GO:0007162	negative regulation of cell adhesion	IMP	J:240585
Biological Process	GO:0007162	negative regulation of cell adhesion	ISO	J:164563
Biological Process	GO:1903904	negative regulation of establishment of T cell polarity	ISO	J:164563
Biological Process	GO:1905872	negative regulation of protein localization to cell leading edge	IMP	J:240585
Biological Process	GO:2001107	negative regulation of Rho guanyl-nucleotide exchange factor activity	IMP	J:240585
Biological Process	GO:2001107	negative regulation of Rho guanyl-nucleotide exchange factor activity	ISO	J:164563
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	ISO	J:164563
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IMP	J:240585
Biological Process	GO:0009968	negative regulation of signal transduction	IEA	J:60000
Biological Process	GO:2000405	negative regulation of T cell migration	ISO	J:164563
Biological Process	GO:0042130	negative regulation of T cell proliferation	ISO	J:164563
Biological Process	GO:0051491	positive regulation of filopodium assembly	ISO	J:164563
Biological Process	GO:0051491	positive regulation of filopodium assembly	IMP	J:240591
Biological Process	GO:0045663	positive regulation of myoblast differentiation	ISO	J:164563
Biological Process	GO:1901741	positive regulation of myoblast fusion	ISO	J:164563
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	IMP	J:240585
Biological Process	GO:2000391	positive regulation of neutrophil extravasation	IMP	J:240585
Biological Process	GO:0051260	protein homooligomerization	IDA	J:234083
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:2000114	regulation of establishment of cell polarity	IMP	J:240585
Biological Process	GO:1901673	regulation of mitotic spindle assembly	ISO	J:164563
Biological Process	GO:0007605	sensory perception of sound	IMP	J:234083
Biological Process	GO:0007605	sensory perception of sound	ISO	J:73065
Biological Process	GO:0048741	skeletal muscle fiber development	IEA	J:72247