GO Annotations Graph

• Symbol: Ppargc1b
• Name: peroxisome proliferative activated receptor, gamma, coactivator 1 beta
• ID: MGI:2444934

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050682	AF-2 domain binding	ISO	J:164563
Molecular Function	GO:0030331	nuclear estrogen receptor binding	ISO	J:164563
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:164563
Molecular Function	GO:0030374	nuclear receptor coactivator activity	IBA	J:265628
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:153416
Molecular Function	GO:0005515	protein binding	IPI	J:129891
Molecular Function	GO:0005515	protein binding	IPI	J:129766
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0003723	RNA binding	IEA	J:72247
Molecular Function	GO:0003712	transcription coregulator activity	ISO	J:164563
Molecular Function	GO:0008134	transcription factor binding	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016592	mediator complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-1605530
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0007015	actin filament organization	IMP	J:146763
Biological Process	GO:0060346	bone trabecula formation	IMP	J:146763
Biological Process	GO:0034614	cellular response to reactive oxygen species	IDA	J:146763
Biological Process	GO:0030520	intracellular estrogen receptor signaling pathway	ISO	J:164563
Biological Process	GO:0006390	mitochondrial transcription	IMP	J:146763
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:146763
Biological Process	GO:0001503	ossification	IMP	J:146763
Biological Process	GO:0010694	positive regulation of alkaline phosphatase activity	IMP	J:146763
Biological Process	GO:0045780	positive regulation of bone resorption	IMP	J:146763
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:116167
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IBA	J:265628
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:146763
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	IMP	J:146763
Biological Process	GO:0042327	positive regulation of phosphorylation	IMP	J:146763
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563