GO Annotations Graph

• Symbol: Phldb2
• Name: pleckstrin homology like domain, family B, member 2
• ID: MGI:2444981

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:249862
Cellular Component	GO:0045180	basal cortex	ISO	J:164563
Cellular Component	GO:0045180	basal cortex	IBA	J:265628
Cellular Component	GO:0031252	cell leading edge	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0045111	intermediate filament cytoskeleton	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0016477	cell migration	IGI	J:249862
Biological Process	GO:0030010	establishment of cell polarity	IGI	J:249862
Biological Process	GO:0045184	establishment of protein localization	ISO	J:164563
Biological Process	GO:0000226	microtubule cytoskeleton organization	ISO	J:164563
Biological Process	GO:0051895	negative regulation of focal adhesion assembly	ISO	J:164563
Biological Process	GO:0051497	negative regulation of stress fiber assembly	ISO	J:164563
Biological Process	GO:1903690	negative regulation of wound healing, spreading of epidermal cells	ISO	J:164563
Biological Process	GO:1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	ISO	J:164563
Biological Process	GO:0010717	regulation of epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0010470	regulation of gastrulation	ISO	J:164563
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	ISO	J:164563
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	IBA	J:265628