GO Annotations Graph

• Symbol: Spg11
• Name: SPG11, spatacsin vesicle trafficking associated
• ID: MGI:2444989

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019901	protein kinase binding	ISO	J:313958
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0030424	axon	IDA	J:213593
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:73065
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:213593
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0030425	dendrite	IDA	J:213593
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0045202	synapse	ISO	J:164563
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0045202	synapse	IMP	J:213593
Biological Process	GO:1905037	autophagosome organization	ISO	J:313958
Biological Process	GO:0008088	axo-dendritic transport	ISO	J:164563
Biological Process	GO:0008088	axo-dendritic transport	IBA	J:265628
Biological Process	GO:0008088	axo-dendritic transport	IMP	J:213593
Biological Process	GO:0048675	axon extension	IBA	J:265628
Biological Process	GO:0048675	axon extension	IMP	J:213593
Biological Process	GO:0007409	axonogenesis	ISO	J:73065
Biological Process	GO:0007268	chemical synaptic transmission	ISO	J:164563
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0033344	cholesterol efflux	IMP	J:274090
Biological Process	GO:0033344	cholesterol efflux	IMP	J:288625
Biological Process	GO:0021957	corticospinal tract morphogenesis	IMP	J:274090
Biological Process	GO:0051668	localization within membrane	IMP	J:288625
Biological Process	GO:0007040	lysosome organization	ISO	J:313958
Biological Process	GO:0007040	lysosome organization	IMP	J:288625
Biological Process	GO:0007040	lysosome organization	IMP	J:274090
Biological Process	GO:0007040	lysosome organization	IMP	J:228803
Biological Process	GO:0007613	memory	IMP	J:274090
Biological Process	GO:0061744	motor behavior	IMP	J:274090
Biological Process	GO:0097049	motor neuron apoptotic process	IMP	J:274090
Biological Process	GO:0007528	neuromuscular junction development	IMP	J:274090
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:274090
Biological Process	GO:0090389	phagosome-lysosome fusion involved in apoptotic cell clearance	IMP	J:228803
Biological Process	GO:0006606	protein import into nucleus	IMP	J:288625
Biological Process	GO:2001256	regulation of store-operated calcium entry	IMP	J:288625
Biological Process	GO:0048167	regulation of synaptic plasticity	ISO	J:73065
Biological Process	GO:0048741	skeletal muscle fiber development	IMP	J:274090
Biological Process	GO:0048489	synaptic vesicle transport	ISO	J:164563
Biological Process	GO:0048489	synaptic vesicle transport	IBA	J:265628
Biological Process	GO:0090659	walking behavior	IMP	J:228803