GO Annotations Graph

• Symbol: Arhgap1
• Name: Rho GTPase activating protein 1
• ID: MGI:2445003

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005096	GTPase activator activity	IBA	J:265628
Molecular Function	GO:0005096	GTPase activator activity	IDA	J:80946
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:73065
Molecular Function	GO:0005515	protein binding	IPI	J:133434
Molecular Function	GO:0017124	SH3 domain binding	IEA	J:60000
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Cellular Component	GO:0031252	cell leading edge	IDA	J:133434
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0010008	endosome membrane	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:98043
Cellular Component	GO:0001726	ruffle	IDA	J:98043
Cellular Component	GO:0097443	sorting endosome	ISO	J:164563
Biological Process	GO:0016197	endosomal transport	ISO	J:164563
Biological Process	GO:2001136	negative regulation of endocytic recycling	ISO	J:164563
Biological Process	GO:2001136	negative regulation of endocytic recycling	IBA	J:265628
Biological Process	GO:0043087	regulation of GTPase activity	IDA	J:80946
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0007264	small GTPase mediated signal transduction	IBA	J:265628
Biological Process	GO:0007264	small GTPase mediated signal transduction	ISO	J:73065
Biological Process	GO:0033572	transferrin transport	ISO	J:164563