GO Annotations Graph

• Symbol: Ccbe1
• Name: collagen and calcium binding EGF domains 1
• ID: MGI:2445053

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0005518	collagen binding	ISO	J:186594
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Cellular Component	GO:0005581	collagen trimer	IEA	J:60000
Cellular Component	GO:0031012	extracellular matrix	ISO	J:186594
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0043542	endothelial cell migration	IMP	J:186594
Biological Process	GO:0030324	lung development	IMP	J:213127
Biological Process	GO:0001945	lymph vessel development	IMP	J:213127
Biological Process	GO:0001946	lymphangiogenesis	ISO	J:164563
Biological Process	GO:0001946	lymphangiogenesis	IMP	J:186594
Biological Process	GO:1904977	lymphatic endothelial cell migration	IMP	J:186594
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045766	positive regulation of angiogenesis	IDA	J:209725
Biological Process	GO:0010595	positive regulation of endothelial cell migration	IMP	J:186594
Biological Process	GO:1901492	positive regulation of lymphangiogenesis	IDA	J:209725
Biological Process	GO:0010954	positive regulation of protein processing	ISO	J:164563
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	ISO	J:164563
Biological Process	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	ISO	J:164563
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	IMP	J:213127
Biological Process	GO:0003016	respiratory system process	IMP	J:213127